Dr. Lee's team publishes another research paper of 2022 in peer-reviewed Neurochemistry journal

Sunghee Lee • March 20, 2022

Every day this past summer was filled with unparalleled excitement and energy in the basement of Cornelia Hall , where the research laboratory of Dr. Sunghee Lee is located. After a one year pause from in-person laboratory investigation in 2020, all members of Project Symphony (the name of Lee's research group) appreciated their opportunity to be immersed once again in hands-on research together, while maintaining safety protocols with facial masks.


Now we are enjoying fruits of these incredible efforts, with another peer-reviewed research article just published. The article is titled "Differential Interaction of Cannabidiol with Biomembranes Dependent on Cholesterol Concentration", in ACS Chemical Neuroscience, a publication of American Chemical Society.


This paper is coauthored by six undergraduates, Escarlin Perez ('22 Biochemistry), Jasmin Ceja-Vega ('23 Biochemistry), Michael Krmic ('22 Biochemistry), Alondra Gamez Hernandez ('23 Biochemistry), Jamie Gudyka ('24 Biochemistry), Riley Porteus ('24 ACS Chemistry), under the mentorship of Dr. Sunghee Lee.


This project deals with the Cannabidiol (CBD) molecule, which has gained increasing attention among the public for its potential health benefits, especially related to certain crippling neurological disorders. Our study investigates the impact that CBD molecules have when interacting with membranes containing different amounts of cholesterol. Using a model of a cell membrane, we demonstrate that there is a sensitivity to the interaction of CBD molecules with cell membranes, depending on the quantity of cholesterol present. The significance of this finding is related to the potential use of CBD in pharmaceutical treatments of neurodegenerative diseases, the kind that are linked to varying levels of cholesterol in the central nervous system.


Congratulations to the project team!

Let's keep the positive energy and momentum going for the summer 2022. 

Celebrating Our Graduating Seniors: A Joyful End-of-Semester Gathering

By Sunghee Lee • May 6, 2025
As the semester comes to a close, Project Symphony members gathered to celebrate a very special milestone - the graduation of seven dedicated seniors who have been an integral part of our team for many years. Their passion, enthusiasm, and hard work have not only driven their individual growth but have also contributed to the collective success of our group. Together, we’ve achieved so much more than any one of us could alone - a beautiful reminder of the power of collaboration and shared purpose...the true meaning of the "Project Symphony"! We want to extend our heartfelt thanks to these remarkable students for the energy and commitment they brought to the lab every day. Your contributions have truly made a difference, and we are proud to have been part of your journey. As you embark on your next chapter, we wish you all the very best in your future endeavors. Remember, once you are a member of the Project Symphony, you are forever part of our family. We look forward to seeing the incredible things you will accomplish ahead! Congratulations and thank you for everything!

Congratulations to Dr. Giancaspro on Earning His Medical Degree!

By Sunghee Lee • May 5, 2025
We are thrilled to celebrate a remarkable milestone for our former Project Symphony group member, Joe, who officially earned their Medical Doctor (MD) degree today for SUNY Upstate Medical University. This achievement marks the culmination of years of dedication, hard work, and passion for advancing healthcare. During his time with Project Symphony, Joe demonstrated exceptional commitment to research and a genuine curiosity that inspired us all. We have no doubt that these qualities will make him an outstanding physician and a valuable contributor to the medical community. Please join us in congratulating Dr. Giancaspro on this well-deserved accomplishment. We look forward to seeing all the incredible ways they will impact the world of medicine!

Celebrating Excellence: A Big Congrats to the Project Symphony

By Sunghee Lee • April 17, 2025
I’m so excited to congratulate and celebrate the amazing achievements of our undergraduate research group, the Project Symphony, at this year’s Iona Scholars Day! You all worked incredibly hard, and it really showed. The presentations covered a wide range of interesting and impactful projects that not only highlight your academic skills but also your passion for learning and discovery. Each project was a great example of your creativity and dedication. What stood out the most was how engaged and enthusiastic everyone was about their research. Your energy was contagious, and it was clear you’ve really connected with your topics and learned a lot along the way. A huge shoutout to each of you for your fantastic presentations. Your hard work and passion for research really set you apart, and I’m so proud of everything you’ve accomplished. I’m confident you’ll keep doing great things and making a real impact in your fields. Once again, congrats to everyone on a successful Iona Scholars Day!
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