New Insights into Serotonin’s Relationship with Cell Membranes
In this study, we explored how the membrane environment shapes the behavior of serotonin, a key neurotransmitter involved in mood regulation and neural signaling. By systematically varying lipid composition in model membranes, we uncovered how differences in lipid charge, fluidity, and packing influence serotonin’s nonspecific interactions with bilayers.
Our findings shed new light on the physical chemistry of neurotransmitter–membrane interactions, with potential implications for understanding serotonin’s diverse physiological functions and its role in receptor signaling.
Congratulations to all co-authors for their outstanding work and collaboration! The article can be accessed here: https://pubs.acs.org/doi/full/10.1021/acsptsci.5c00767




