Spreading Iona Science to the World: Fifteen Project Symphony Members Attend the National Meeting of the American Chemical Society in Chicago, IL

Sunghee Lee • August 30, 2022

After an exciting research experience in summer ‘22 spent mostly in the Cornelia Hall laboratory, a team of fifteen Project Symphony members traveled to Chicago, IL and presented at the National Meeting of the American Chemical Society (ACS) with their faculty mentor, Dr. Sunghee Lee of the Chemistry & Biochemistry Department. The theme of this year's ACS meeting was "Sustainability in a Changing World", which highlighted the critical role that Chemists play in addressing our environmental challenges, and how academia, industry, and government can work together to help create a more sustainable world. The Project Symphony team was honored to be part of an international conference, participated in sessions, workshops & networking opportunities, and presented seven research papers at Biomaterials & Biointerfaces session of the Division of Colloid and Surface Chemistry:

#1. Differential Interaction of Cannabidiol with Biomembranes Dependent on Cholesterol Concentration

#2. Characterization of electrical properties of model lipid membranes using a modified electrophysiological technique

#3. Calculations of DOPC/DOPE Bilayer Structural Properties at Different Compositions by Molecular Dynamics Simulation

#4. Effects of plant polyphenols on biophysical properties of model membranes

#5. Raman spectroscopic investigation of model lipid membranes containing cholesterol and small molecules

#6. Thermodynamic investigation of interactions of phytochemicals with model cell membranes 

#7. Effect of different DOPC/DOPS Ratios on the Structural Properties of Biological Membranes 



By Sunghee Lee September 2, 2025
We are absolutely thrilled to announce that our Project Symphony, undergrad-fueled research team, just published another article digging into how those stubborn “forever chemicals”, called perfluoroalkyl substances, or PFAS, can mess with model bacterial membranes, making them leakier and less organized than before. It is alarming to discover that these chemicals actively change the physical properties of membranes, and different types of lipids respond in their own way to the disruption, meaning some bacteria could be more affected than others. What makes this work even more special is that our undergraduate team handled every step, and it’s now out there as open access for everyone to read—proof that curiosity and teamwork can lead to great science. The article is appeared in ACS Omega (on August 26, 2025), a publication of American Chemical Society (ACS). Please explore the article here: " Membrane-Modifying Effects of Perfluoroalkyl Substances in Model Bacterial Membranes " https://pubs.acs.org/doi/10.1021/acsomega.5c04177 Congratulations to Micaela, Amani, Jasmin, Jessica, Lizzy, Joey, and Jacqui for their enthusiasm and hard work leading to this contribution! Project Symphony’s journey continues—stay tuned for what’s next.
By Sunghee Lee August 21, 2025
We are incredibly proud to announce that our talented Project Symphony undergraduate research team has just published a significant scientific article in the prestigious Journal of Physical Chemistry B, a leading journal published by the American Chemical Society in physical chemistry research. The newly published study, titled "Biophysical Consequences for Exposure of Model Cell Membranes to Perfluoroalkyl Substances," explores the complex interactions of widely used environmental chemicals (PFAS) with biological model membranes. This research addresses important health and environmental questions, employing various techniques to reveal how molecular structures of PFAS influence membrane properties and permeability. Please read: Biophysical Consequences for Exposure of Model Cell Membranes to Perfluoroalkyl Substances, J. Phys. Chem. B 2025, 129, 31, 7951–7963 https://pubs.acs.org/doi/10.1021/acs.jpcb.5c02472 What makes this achievement truly exceptional is that the work was led and conducted by undergraduate researchers, demonstrating their brilliance and dedication to advancing scientific knowledge. Their contribution not only adds valuable insights into the field of environmental and physical chemistry but also sets an inspiring example of how undergraduate students can make impactful contributions to cutting-edge science. Congratulations to the entire team for this outstanding accomplishment! This publication is a testament to their hard work, curiosity, and the rigorous training they have received.
By Sunghee Lee May 6, 2025
As the semester comes to a close, Project Symphony members gathered to celebrate a very special milestone - the graduation of seven dedicated seniors who have been an integral part of our team for many years. Their passion, enthusiasm, and hard work have not only driven their individual growth but have also contributed to the collective success of our group. Together, we’ve achieved so much more than any one of us could alone - a beautiful reminder of the power of collaboration and shared purpose...the true meaning of the "Project Symphony"! We want to extend our heartfelt thanks to these remarkable students for the energy and commitment they brought to the lab every day. Your contributions have truly made a difference, and we are proud to have been part of your journey. As you embark on your next chapter, we wish you all the very best in your future endeavors. Remember, once you are a member of the Project Symphony, you are forever part of our family. We look forward to seeing the incredible things you will accomplish ahead! Congratulations and thank you for everything!
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