Published: Ibuprofen and the Phosphatidylcholine Bilayer: Membrane Water Permeability in the Presence and Absence of Cholesterol
Sunghee Lee • April 9, 2021
The research group of Dr. Sunghee Lee has just published a peer-reviewed research article, titled “
Ibuprofen and the Phosphatidylcholine Bilayer: Membrane Water Permeability in the Presence and Absence of Cholesterol”, appearing in Langmuir, a publication of American Chemical Society. This project is a result of another harmonious team effort, and is coauthored by nine undergraduates, Megan Wood (’19 Biochemistry), Michael Morales ('19 Biochemistry), Elizabeth Miller (’19 Biochemistry), Samuel Braziel (’18 Chemistry), Joseph Giancaspro ('20 Biochemistry), Patrick Scollan ('20 Chemistry), Juan Rosario ('20 Biochemistry), Alyssa Gayapa ('19 Chemistry), Michael Krmic ('21 Biochemistry), and Dr. Lee. This article investigates the impact that the drug Ibuprofen has on the properties of model cell membranes in the presence and absence of cholesterol, including any changes in water transport properties and structural perturbation using various biophysical chemistry methods. Congratulations to the research team!
Project Symphony members proudly presented seven research posters at the ACS Fall Meeting in Chicago in the Biomaterials and Biointerfaces session of the Division of Colloid and Surface Chemistry. Presenting in this highly professional research setting—alongside graduate students and Ph.D.-level chemistry researchers—was a meaningful opportunity for our students to share their work, exchange ideas, and represent Project Symphony. This year’s group photograph is especially meaningful because it includes two Project Symphony alumni from the classes of 2015 and 2010, pictured at the far left and far right. Both are now accomplished scientists, and their return is a wonderful reminder of the lasting legacy of Project Symphony and the close-knit scientific community we have built over the past two decades. I am immensely proud of the hard work, dedication, and growth that led to these presentations. Congratulations to all of our presenters—keep up the excellent work!
We are proud to celebrate the continued success of former Project Symphony member Colleen Clarke, a Ph.D. candiate at Clemson University, who has recently received the first place in the poster session at the Women in the Global Battery Industry's Science Award. Colleen received this prestigious honor for her academic work on the impact of lignin on the transport of chemical properties of sulfonated ionomer composites for all-vanadium redox flow batteries. Colleen exemplifies the curiosity, dedication, and perseverance that Project Symphony strives to nurture in all of its participants. During her time with Project Symphony, Colleen demonstrated a strong commitment to scientific exploration and collaborative learning. Those early experiences helped shape her path toward advanced study and research, where she continues to excel and make meaningful contributions in her field. We are thrilled to see her accomplishments and look forward to following her continued success. Congratulations, Colleen—we are incredibly proud of you!
On Thursday, April 16, 2026, our Project Symphony members presented their work at the 17th annual Iona Scholars Day, a campus-wide celebration of student scholarship and creative activity. This event showcases faculty-mentored projects across disciplines and highlights the depth of undergraduate research at Iona. This year, Project Symphony members contributed an impressive total of 15 research posters, representing months—and in many cases, years—of sustained effort, curiosity, and collaboration. Their work stood alongside projects from across the university, helping to put chemistry and biophysical research in the spotlight. As the PI of Project Symphony, I am deeply proud of each team member’s dedication, professionalism, and growth. Watching them explain complex ideas with clarity and confidence to faculty, peers, and visitors was truly inspiring. Their posters did more than present data—they told the story of how careful experimentation, persistence, and teamwork lead to new insights. Congratulations again to all of our presenters—you represented Project Symphony, with excellence.
